Benign prostatic hyperplasia (BPH) is the enlargement of the prostate caused by an overgrowth of cells (called hyperplasia) in the transition zone of the prostate around the urethra. BPH is one of the most common male diseases and is provoked by dihydrotestosterone and androgen signals. These androgen signals trigger overexpression of different factors that initiate excessive growth and inflammation within the prostate. Statistics indicate that by 70 years of age, almost all men will have some amount of prostate enlargement.

However, men with BPH may not have any signs or symptoms. If signs and symptoms do develop, they most often happen in men older than 50 years of age. Signs and symptoms of BPH start when the enlarged prostate puts pressure on the urethra and bladder. This can narrow (constrict) or block the urethra, which can cause changes in bladder habits and problems urinating.

BPH can cause the following, which are sometimes called lower urinary tract symptoms (LUTS):

  • difficulty passing urine
  • more frequent urination (called urinary frequency), especially at night
  • a strong or sudden urge to urinate (called urinary urgency)
  • weak or slow urine stream
  • being unable to empty the bladder completely, which can lead to urinary tract infections and bladder stones
  • difficulty starting the urine stream (called straining)
  • having difficulty controlling the bladder (called incontinence), which can cause urine to leak and dribble
  • blood in the urine

Toulison Nutraceuticals Inc. has recently developed a highly efficient natural product, called Healthy Prostate Tincture. This liquid supplement can be used for both, BHP prevention, and treatment. Our product for prostate health is highly purified herbal extract mixture of two major components: organic turmeric (Curcuma longa) and organic stinging nettle (Urtica dioica). Both tincture ingredients complement to each other and provide a profound and stable improvement for people with BHP.

So, how does this product actually work? Turmeric (a spice, widely used in Asian Cuisine) is known as a very powerful anti-oxidant and anti-inflammatory substance. There is a significant body of studies showing that these properties are determined by turmeric’s ability to inhibit mitogenic and proinflammatory factors, such as IGF1, VEGF and TGF-ß1. These factors are the main triggers in developing BHP and therefore, the main targets to be inhibited in order to stop the process of prostate enlargement.

The other Healthy Prostate Tincture component, is the extract of stinging nettle.  While turmeric is suppressing mitogenic and pro-inflammatory factors, active ingredient of stinging nettle prevents binding testosterone to the sex hormone binding globulin (SHBG). This sex hormone globulin is involved in the hormones transportation through the plasma and their delivery to receptors in various target organs including the prostate. When testosterone is unable to bind to this globulin, the prostate receives far lower amounts of the hormone. In addition, testosterone metabolites such as DHT (dihydrotestosterone, also implicated in the enlargement of the prostate), cannot get to the prostate. As a result, excessive androgen stimulation of the prostate is prevented and the symptoms of BPH are relieved.

For more information about Toulison Nutraceuticals Inc’s Healthy Prostate Tincture, or to order this amazing product, visit us at www.toulison.com

 

 


Eczema is a chronic inflammatory skin condition, characterized by dry skin with patches that are red and intensely itchy. The eczema patches may ooze, become scaly, crusted, or hardened. Symptoms can range from mild to severe and the condition can negatively impact quality of life. People with eczema tend to have an over-reactive immune system that when triggered by a substance outside or inside the body, responds by producing inflammation. It is this inflammation that causes the red, itchy and painful skin symptoms common to most types of eczema. Emotional stress is also considered an eczema trigger. Some people’s eczema symptoms get worse when they’re feeling “stressed”. Others may become stressed, just knowing they have eczema, and this can make their skin flare up. Regardless what the initial trigger is, the biological pathway is still the same – overreaction of immune system with overexpression of certain biologically active substances that can turn the inflammation and eczema process on.

Recently Toulison Nutraceuticals Inc. developed a new product called “Eczema Healing Cream”. The main cream ingredient is extract from Spirulina, a superfood plant that is known as an enriched source of protein, minerals, vitamins, and antioxidants. Another benefit of this herbal supplement is that it can inhibit non-specific auto-immune reactions (an essential trigger of eczema) and keep those reactions under control (research data obtained by Toulison Nutraceuticals Inc.). This new product for treating eczema symptoms is a smooth and easy applying cream that starts working right away and gives a complete recovery after 4 weeks of regular applications. Below you can see the results obtained by a client with a severe eczema case (hands and legs affected), when using Dr. Toulina’s Eczema Healing Cream.

Figure 1:

Figure 2:

Figure 3:

Figure 4:

To obtain more information about this innovative unique product to cure eczema, please visit our website www.toulison.com


UV photons can mediate damage through two different mechanisms. It could be either by direct absorption of UV via cellular chromophores, resulting in excited states formation and subsequent chemical reaction, or by photosensitization mechanisms, where the UV light is absorbed by endogenous (or exogenous) sensitizers that are excited and whose further reactions lead to formation of reactive oxygen species (ROS). Direct and indirect injuries result in a number of harmful effects, such as disrupted cell metabolism, morphological and ultrastructural changes, attack on the regulation pathways and alterations in the differentiation, proliferation and apoptosis of skin cells.  UV radiation is known to have significant adverse effects including immunosuppression, photoaging, ocular damage, and skin cancer.

The modern skin care market offers lots of sunscreen products; however, the safety aspect of added components stays pretty doubtful and unclear. For instance, one of the main ingredients commonly used in sun protective products, is Octyl Methoxycinnamate, which according to the Cosmetics Database is rated as 70% safe. However, there are many concerns regarding its use some of each include: biochemical changes that cause mutation and cell death upon exposure to sunlight (which is likely when used as a sunscreen ingredient); immunotoxicity and photoallergic effects. Another widely used component in sunscreen care products is Oxybenzone. This substance is clearly a prolific ingredient, and it is worthwhile to look into the potential dangers of something that finds its way into the majority of people’s bodies. The Environmental Working Group has been rated oxybenzone at number 8 on their toxicity rating scale, meaning it is one of the most toxic ingredients found in cosmetic products.

We are happy to report that Toulison Nutraceuticals Inc. has recently developed natural sunscreen Ginkgo biloba cream, the product that protects skin cells from the damaging UV radiation without any toxic side effects. Our company performed lots of experiments carried on adult human skin fibroblasts to test the sunscreen capacity of new formulation with Ginkgo biloba herbal extract as an active ingredient. Among different biochemical assays, we used cell proliferation technique to evaluate the capacity of human skin fibroblasts to maintain their proliferative activity. For this purpose, cells were radiated with UV light to induce oxidative stress. We compared samples with added Ginkgo biloba extract and without it. We also checked to see if adding Ginkgo biloba extract prior UV radiation was more effective than adding extract after UV exposure. The results show that Ginkgo biloba extract increased cell proliferation up to 88% (compared to control) when added before cells exposure with UV radiation and up to 50% ( compared to control) when the extract was added after cells were undergone UV treatment (Fig. 1 – below)

Our skin sun protector Ginkgo biloba cream is exactly what everyone needs in these hot sunny days to maintain skin moisturized and protected from damaging UV effect. According to our results, an optimal effect can be reached by applying cream on openly-exposed parts of body before going outside, as it will provide maximum protection from UV radiation.

We invite you to try our products to embrace care and safety coming from natural formulations designed by Toulison Nutraceuticals Inc.

To order this product online, please visit our website at the link listed below:

https://www.toulison.com


Most of us find our first “greys” by the time we turn 30, usually at the temples, then later, across the scalp.  The grey hair “rule of thumb” is that by the age of 50, half of the population have lost the color in 50% of their hair. When researchers tested this rule, they found that 74% of people aged between 45 and 65 had grey hair, with an average intensity of 27%.

Hair color is produced by cells known as melanocytes, which migrate into the hair bulb as the hair follicles develop in utero. The melanocytes produce pigment that is incorporated into the growing hair fibers to produce hair in a bewildering array of natural shades.

Hair color depends on the presence and ratios of two groups of melanin types: eumelanin (brown and black pigments) and pheomelanin (red and yellow pigments). While variations in the ratio of these pigments can produce a large number of colors and tones, this explains the variety of natural hair color.

So, what happens when our hair turns grey and why doesn’t pigment production turn back on?

At the end of each hair cycle, some pigment-producing melanocytes become damaged and die. If the melanocyte stem cell reservoir at the top of the hair follicle can replenish the bulb, this keeps pigment production going. But when the reservoir of stem cells is exhausted, pigment production stops and the hair turn grey. In order to prevent hair from going grey, it would need to either prolong the life of the melanocytes in the hair bulb – by protecting them from injury – or expand the melanocyte stem cell reservoir in the upper or top region of the hair follicle so they continue to replace lost pigment cells.

Toulison Nutraceuticals Inc. has identified a series of plant derived compounds that protect hair follicle melanocytes from damage at the end of the hair cycle. This enables pigment production to restart as soon as the next hair cycle begins.

The compounds work by mimicking the action of an enzyme called DOPA-chrome tautomerize. This enzyme is the naturally occurring antioxidant in the hair bulb that protects melanocytes from oxidative damage. By duplicating the effects of DOPA-chrome tautomerize, melanocyte metabolism and survival improves.

The new agents are being formulated into a product, called Hair Growth Enhancer, that can be applied as a spray-on hair root. This product will not re-color grey hair or bring back the dead cells that produce hair color but will protect your melanocytes. The newly developed Hair Growth Enhancer not only reverses the hair color but also reduces the hair loss, improves the hair look and thickens the hair strands due to increased keratin production.

Below we present our data about an incredibly beneficial effect of our Hair Growth Enhancer on hair. In our experiments, this product significantly increased the hair thickness up to size of regular colored hair (Fig.1,2). After treatment with Hair Growth Enhancer, the grey hair increased the same thickness as regular colored hair.

Fig. 1

Fig. 2

Due of capacity of melanin (both eumelanin and pheomelanin) to provide autofluorescence, we took fluorescent microcopy images for untreated grey hair, grey hair treated with our product (for 4 weeks) and regular colored hair to witness any differences in levels of melanin production. On a picture below, you can see an increase of intensity of fluorescence (which means an increase of melanin production) in grey hair treated with the Hair Growth Enhancer in comparison with untreated grey hair.

We invite you to try our magnificent Hair Growth Enhancer to experience lots of benefits in order to have naturally beautiful and healthy hair. Please, visit our website to order this product on-line and get introduced to a variety of different other products our company offers to their customers at www.toulison.com


The first week of April of 2018 was groundbreaking for Toulison Nutraceuticals Inc. and its team members!  The company has participated at the Green Living Show that pairs the sellers of different natural goods with the shoppers looking for new products and ideas. It was also the first time TNI has advertised and sold its products outside the usual Internet environment. Although the initial participation is often more educational than lucrative, some of the TNI products (such as “Colloidal Silver Water”) were completely sold out during the event. That serves as a strong indication of the public interest in natural solutions that represent effective and gentle ways of taking care of the human body.  Other products that TNI has presented and sold during the show include: Turmeric Healing Facial and Acne cream, Aloe Vera Eye cream, Gingko Biloba Sunscreen Day cream, Black Rice Extract Night cream and Resveratrol Night cream. This is not a complete list of products designed by Toulison Nutraceuticals. Stay young, happy and healthy with Toulison Nutraceuticals Inc. and Mother Nature!  To get more information and/or to place an order, please visit our website at www.toulison.com

  

The Toulison – Green Living Show Booth

Toulison Research Information booklets

Toulison Products on display

Victoria with visitors to our booth

The Toulison Team.

 

 


Cream Industry Ingredients – Appalling Findings

On my way home I was stopped by cosmetic products distributor and given samples of face cream manufactured by a very famous skin care product company. While looking at the sample, I noticed that there was a warning saying that you need to avoid contact of this cream with your eyes and if it happened there was a recommendation to rinse your eyes thoroughly.

This warning made me start exploring the cream’s content and that is what I found out.  The image of the back of the cream container is enclosed in this report. For courtesy reasons, we will not disclose the company or company’s brand name. However, we would encourage you to pay close attention when buying any skin care products, even if they are manufactured by a well-established and respected company.

There are a few ingredients specified on a cream label that are a subject of serious concerns.

1)ISOHEXADECANE

  • Isohexadecane is classified as expected to be toxic or harmful. Suspected to be an environmental toxin and be persistent or bio-accumulative.

2) Dimethicone

  • Dimethiconeis a synthetic oil made from two different types of silicon polymers, D4 and D5. It is used primarily as a skin and hair conditioner. Manufacturers like it because it adds a gliding feel to lotions and creams. It also forms a lasting barrier on the skin that can fill in fine lines and wrinkles.

The downsides to this ingredient are many:

  • Silicone and its derived ingredients are occlusive, meaning they don’t let oxygen through.
  • Dimethicone reduces normal and necessary skin functioning. The artificial coating of dimethicone on the outside of skin interferes with the skin’s natural ability to eliminate toxins coming out of the body. Recent studies show that prolonged exposure of the skin to its own sweat, because of occlusive substances like dimethicone, can cause skin irritation and impair cell development.
  • The European Union has found D4 to be an endocrine disruptor based on evidence it interferes with human hormone function and as a possible reproductive toxicant that may impair human fertility. Lab animal experiments using high levels of D5 have caused uterine tumors and harm to the reproductive and immune systems. D5 also showed an ability to influence neurotransmitters in the nervous system.
  • Dimethicone is not biodegradable. In Canada this ingredient has been shown to be persistent in the environment and to accumulate in aquatic organisms. Environment Canada and Health Canada have proposed adding D4 and D5 to the “List of Toxic Substances” and to limit the quantity of D4 and D5 in personal care products.
  • Prolonged exposure to dimethiconecan actually increase skin irritation, due to the coating property and because dimethicone is listed as a possible skin and eye irritant. Those with sensitive or reactive skin are at risk of an allergic reaction to dimethicone.

3) Phenoxyethanol

  • The Material Safety Data Sheet (MSDS) on phenoxyethanolstates that it can cause skin and lung irritation. It’s also toxic to the kidneys, nervous system, and liver, and repeated, long-term exposure can cause organ damage. It notes that toxic effects can occur through inhalation, skin exposure, and ingestion.

4) Disodium EDTA

  • EDTA is a chemical created from the combination of formaldehyde, sodium cyanide, and ethylene diamine. This chemical is added to many sodas, processed foods including sandwich spreads, salad dressings, sauces and numerous canned or pickled foods.
  • There is limited data about the true safety of EDTA in food and cosmetics. Some advocates of the preservative state that the chemical does not reach a level of toxicity in humans until 2.5 – 3 grams and may be considered to be a danger when consumed for several consecutive days. Additionally, some scientists suspect that it is a persistent organic pollutant (POP). In that case, each intake would only be partially excreted, while the remaining part builds up in the body. Thus, long-term exposure to disodium EDTA would potentially create toxicity in the body. Environmental lists have similar concerns regarding the eliminated portion of the POP and its inability to be broken down.
  • When used as a medicinal chelating agent there are several possible adverse effects. There is the possibility of depletion of important metals/vitamins, hypotension, headaches, migraines, abdominal discomfort, and the lowering of blood sugar. More troubling is the long-term risks of toxicity and kidney damage. An additional concern is attributed to the unknown side effects of the possible build up in the body over time.

As a whole, people are using more artificially preserved items now than ever before in history. The collective overuse of many toxic and carcinogenic chemicals creates a problem for researchers in ascertaining which destructive substances are responsible for specific long-term side effects.

 


Resveratrol came to scientific attention during the mid-1990s. Since then, it has been touted by manufacturers and examined by scientific researchers as an antioxidant, an anti-cancer agent, and a phytoestrogen. Commonly called “The French Paradox in a bottle,” resveratrol is a beneficial compound found in red wine that is associated with life extension and other important health benefits. Resveratrol is naturally produced in grapes as a defence against toxins, and is abundant in the grape skins. As a nutraceutical, resveratrol has multiple benefits. The major of them are:

–  Anti-aging

– Anti- cancer

Recently, the TNI R&D Department has completed an in vitro phase of testing on resveratrol as an anti-cancer and anti-aging compound. Below is some of the data we collected during our study.

Anti-Cancer Properties of Resveratrol

There are two main characteristics that are typical for malignant cells:

  1. An increased ability of cells to proliferate, that allows the tumor grow rapidly
  2. A capacity of cells to migrate and cover a distance as a result of epithelium-mesenchymal transition (EMT) – cell phenotype changes, which lead to metastasis in other organs of the body.

In terms of these two features typical for cancer, our R&D Department tested both characteristics in different types of cancer cells treated with trans-resveratrol, the substanace we mentioned above. Anti-proliferative effect of trans-resveratrol solution was evaluated on the following cancer cell lines: breast cancer, prostate cancer, pancreatic carcinoma and skin fibrosarcoma.  The obtained results are presented on Fig 1.

Figure 1

 

 

 

 

 

 

With all these tested types of cancer, we observed inhibition of proliferation after adding resveratrol solution to cells media, with a maximum inhibition in prostate cancer cells.

To explore a capacity of trans-resveratrol to prevent potential metastatic dissemination of cancer cells,  we performed the “wound scratch assay” on breast cancer cell line. This assay allows to evaluate the process of epithelium-mesenchymal transition (ETM), related to metastatic dissemination of cancer cells all over the body. Our data are presented in Fig 2. According to these graphs, trans-resveratrol significantly inhibited/blocked the process of cell migration with maximum observed within the 48 hour time point. This allows us to consider resveratrol as a potentially beneficial nutraceutical compound with profound anti-cancer properties. More studies are on the way.

Figure 2

 

 

 

 

 

 

Anti-Aging & Rejuvenating Properties of Resveratrol

In order to test anti-aging and rejuvenating effects of resveratrol on normal skin cells we compared the effect of this compound on proliferation in normal skin cells and cancer skin cells. Our goal was to detect whether there is any selectivity in targetting cancer cells by resveratrol. We also wanted to be sure that there was no toxic effect of resveratrol on normal skin cells. Our data are presented in Fig 3 and Fig 4 consequently.

In Fig. 3 we can observe the differences in cells morphology (density, share, size).

Normal cells, treated with resveratrol had bigger size, higher cell density and more regular shape (b) than cancer cells ( lower density, irregular shape, reduced size all of which can be considered as signs of cell apoptotic changes) (a).

Figure 3

          

3a) Normal skin cells_resveratrol   3b) Cancer skin cells_resveratrol                        

Our data is presented in Fig. 4. After 48 hours of incubation, resveratrol was able to increase the proliferation in normal skin cell up to 40 %, while in cancer skin cells resveratrol inhibited proliferation up to 40%.

This data shows that resveratrol is selectively targeting and inhibiting growth of cancer cells, while enhancing/ increasing growth of normal skin cells, which makes it a great candidate for adding to rejuvenating and anti-aging skin care products.

Figure 4

Based on the properties of trans-resveratrol tested in-house on human skin fibroblasts, the TNI then developed a product called Resveratrol Night Cream that incorporates a great combination of natural oils, preservatives and extract of trans-resveratrol powder.

To experience the incredibly beneficial power of this skin care cream, please visit our website and order this product at: https://www.toulison.com/product-page/resveratrol-night-cream


Rosemary (R. officinalis) is a widely used herb that originates from the Mediterranean region. It dates back to the ancient Greeks who hailed the plant for assisting memory and stimulating the brain. The plant contains an essential oil that is needed for survival and known to boost memory. Rosemary is known to have one of the highest properties of spices and can combat fungus, bacteria and cancer.

Rosemary is made up of a wide variety of oils, phenolic acid derivatives, and phenolic diterpenes including:

Oils: 1,8-cineole, α-pinene, camphene, α-terpineol, borneol with antioxidant, antimicrobial, and anticancer effects.

– Phenolic acid derivatives:

– Rosmarinic acid, found heavily in the leaves, protects the lungs and fights Alzheimer’s.

– Carnosic acid, which protects the brain and has strong antioxidant properties.

 

1) Rosemary improves brain function and protects the brain

In a clinical study of 144 volunteers, aromatherapy with rosemary improved working memory performance, memory quality, and increased alertness. In another trial of 28 elderly subjects, low doses (750 mg) of rosemary powder improved memory speed. Rosemary tea also has shown to reduce depression in mice. Carnosic acid protects neurons from oxidative stress and over-stimulation. It builds up in nerve cells and other protective cells in the brain, as well as protects part of the brain (middle cerebral artery) from tissue damage like, ischemia/reperfusion injury. It reduces blood clots and brain swelling in rats.

Carnosic acid protects against oxidative stress, which can cause Alzheimer’s and reduces cell death in rat brains (hippocampus).

Rosemary also prevents beta-amyloid plaques, one of the leading causes of Alzheimer’s disease.

2) Rosemary can fight cancer

In human ovarian cancer cells, some active rosemary constituents stopped cancer cell growth and killed existing cancer cells. There is a vast array of data supporting rosemary’s effectiveness against varieties of cancers including: leukemia, colon, pancreas, breast, prostate, ovaries, cervix, bladder, liver, lung.

Recently, Toulison Nutraceuticals Inc.  R&D department completed the in vitro phase of testing different natural compounds (mostly derived from plants)  on various human cancer cell lines to determine their response and possible selectivity to phytodrugs. In our studies, we discovered that rosemary extract was effective in inhibiting proliferative activity in tested breast and prostate cancer cells during 24 hours of treatment (Figure 1). We also found out that non-cancer cells ( embryonic kidney) responded to this treatment by increasing proliferative activity. This could be a result of “selective targeting” cancer cells by the rosemary extract. More studies are on the way.

3) Rosemary protects the skin

In a study of 10 healthy subjects, rosemary extracts protected the skin from UV damage, increasing its effectiveness with time. More skin cells survived in the volunteers who received rosemary extracts. This protection helps reduce aging, cancer, or UV light damage.

Rosemary oil is also effective against bacteria (P. acnes) that causes acne.

4) Rosemary improves asthma

In a clinical study of 40 asthma patients, rosemary extracts decreased asthma symptoms such as: wheezing, chest pain, coughing, production of sputum (mixture of saliva and mucus).

Additionally, rosmarinic acid and rosemary extracts decreased the production of asthma-induced inflammatory cells (eosinophils, neutrophils, and mononuclear cells) in rats.

5) Rosemary limits weight gain

In rats fed high-fat diets, rosemary extracts decreased weight gain by 64% and fat gain by 57% compared to controls.

Another study found similar results (69% improvements compared to the controls). While the extract did not decrease food intake, it increased fat loss.

6) Rosemary is antimicrobial

Rosemary extracts completely stopped bacterial growth in multiple strains of bacteria (Gram-positive and Gram-negative). The effects were more pronounced for the Gram-positive bacteria. In one study, extracts were able to inhibit 28 of 29 bacterial strains studied. Rosemary also has antifungal properties. Carnosol is a non-toxic compound of rosemary that also has antiviral properties. However, it was not as effective as the rosemary extract.

7) Rosemary has anti-inflammatory properties

At higher doses, rosemary extracts decreased the production of inflammatory molecules (such as IL-1β, COX-1, TNFa, and iNOS) in human cells. It decreases the production of nitric oxide, a product of inflammation.

Rosemary essential oil significantly reduced white blood cell (leukocyte) rolling, another process of the inflammatory response.

8) Rosemary prevents blood clots

Cell and mice studies found that rosemary possessed antithrombotic effects, meaning it stopped blood from clotting and restricting blood flow.

This effect was most likely because rosemary stops platelets activity, which are the molecules responsible for the clotting of blood.

9) Rosemary reduces pain

In traditional medicine, rosemary has been used to fight painful menstruation (dysmenorrhea), especially stomach cramps and kidney colic pain, which is pain caused by blockage of urine from the kidney to the bladder.

10) Rosemary helps grow hair

In a clinical study of 50 patients with androgenic alopecia (permanent balding), rosemary oil significantly increased hair counts after six months.

Toulison Nutraceuticals Inc. R&D department has recently developed the formulation that helps promote hair growth in cases of hair loss, regardless of its cause. Rosemary extract is one of the components in our product.

For more information about this product, please check our website:

https://www.toulison.com/product-page/hair-growth-enhancer

11) Rosemary combats arthritis

Rosemary combats the progression of rheumatoid arthritis by reducing oxidative damage to the joints and surrounding tissues.

Dosage

A meta-analysis found doses of rosemary extract at 0.1-100 μg/mL to be most effective in fighting cancer. However, an effective dose for human use has not been established due to the wide range of concentrations used in different studies.

Overall, the rosemary plant is classified as safe by the FDA. It is found to have very low toxicity in rats, even when used at high concentrations and over extended periods of time.

It is recommended to take 4-6 g of rosemary dry leaf/twig supplements daily and 2-4 mL of liquid extracts three times daily.

The information in this article has not been evaluated by the Food & Drug Administration or any other medical body. Information is shared for educational purposes only.

 


Commercial skin care products are typically loaded with preservatives to allow them to remain fresh during the long span between the time of manufacture and the time the customer finishes using it. Although the preservatives do extend the longevity of the products and help keep them free from bacteria, the preservatives themselves are often unhealthy. Many cause or promote skin problems, and some are even reported to cause cancer. Individuals who are sensitive to these preservatives need to find preservative-free products.

If you thought the FDA does a decent job in regulating what goes into our food supply, you’ll be equally expecting, if not more, on its regulation of cosmetic and personal care products. The same way you look at food labels, you should do the same for your beauty products.

There are thousands of chemicals in your products, many of which are being absorbed into your body. The companies have cart blanche to use any ingredient or raw material without government review or approval.

This industry is highly unregulated. There is no pre-product approval before a product hits the market and enters your home. A minuscule approval process exists, but only for color additives and ingredients classified as over-the-counter drugs.

Many of these synthetic chemicals are skin irritants, skin penetrators, endocrine disrupters and are carcinogenic. I can’t go through all of these harmful chemicals, but here are  10 you should highly avoid:

Parabens. Parabens are widely used preservatives that prevent the growth of bacteria, mold and yeast in cosmetic products. Sounds good, right? Not so fast, they do more than that. Parabens possess estrogen-mimicking properties that are associated with an increased risk of breast cancer. These chemicals are absorbed through the skin and have been identified in biopsy samples from breast tumors. They can be found in makeup, body washes, deodorants, shampoos and facial cleansers. You can also find them in food and pharmaceutical products.

Synthetic colors. If you take a look at your product label and notice FD&C or D&C, they represent artificial colors. F — representing food and D&C representing drug and cosmetics. These letters precede a color and number (e.g., D&C Red 27 or FD&C blue 1). These synthetic colors are derived from petroleum or coal tar sources. Synthetic colors are suspected to be a human carcinogen, a skin irritant and are linked to ADHD in children. The European Classification and Labelling considers it a human carcinogen, and the European Union has banned it.

Fragrance. This particular category is pretty scary because what does “fragrance” mean anyway? This term was created to protect a company’s “secret formula.” But as the consumer, you could be putting on a concoction that contains tons of chemicals that are hazardous to your health. According to the Environmental Working Group (EWG) Skin Deep Database, fragrance mixes have been associated with allergies, dermatitis, respiratory distress and potential effects on the reproductive system. It can be found in many products such as perfume, cologne, conditioner, shampoo, body wash and moisturizers.

Phthalates. A group of chemicals used in hundreds of products to increase the flexibility and softness of plastics. The main phthalates in cosmetics and personal care products are dibutyl phthalate in nail polish, diethyl phthalate in perfumes and lotions, and dimethyl phthalate in hairspray. They are known to be endocrine disruptors and have been linked to increased risk of breast cancer, early breast development in girls, and reproductive birth defects in males and females. Unfortunately, it is not disclosed on every product as it’s added to fragrances (remember the “secret formula” not listed), a major loophole in the law. They can be found in deodorants, perfumes/colognes, hair sprays and moisturizers.

Triclosan. Tricolsan is widely used antimicrobial chemical that’s a known endocrine disruptor — especially thyroid and reproductive hormones, and a skin irritant. Studies raise concerns that triclosan contributes to making bacteria antibiotic-resistant. There also wasn’t enough supporting evidence that washing with antibacterial soaps containing triclosan provides any benefit over washing with regular soap and water. Tricolsan can be found in toothpastes, antibacterial soaps and deodorants.

Sodium lauryl sulfate (SLS) / Sodium laureth sulfate (SLES). This surfactant can be found in more than 90 percent of personal care and cleaning products (mostly foaming products). SLS’s are known to be skin, lung, and eye irritants. A major concern about SLS is its potential to interact and combine with other chemicals to form nitrosamines, a carcinogen. These combinations can lead to a host of other issues like kidney and respiratory damage. They can be found in shampoo, body wash/cleanser, mascara and acne treatment.

Formaldehyde. Formaldehyde and formaldehyde-releasing preservatives (FRP’s) preservatives are used in many cosmetic products to help prevent bacteria growth. This chemical was deemed as a human carcinogen by The International Agency for Research on Carcinogens (IARC) and has been linked to occupation-related cancers: nasal and nasopharyngeal. It is known to cause allergic skin reactions, and it may also be harmful to the immune system. It can be found in nail polish, body washes, conditioners, shampoos, cleansers, eye shadows, nail polish treatments.

Toluene. A petrochemical derived from petroleum or coal tar sources. You may see it on labels listed as benzene, toluol, phenylmethane, methylbenzene. Toluene is a potent solvent able to dissolve paint and paint thinner. It can affect your respiratory system, cause nausea and irritate your skin. Expecting mothers should avoid exposure to toluene vapours, as it may cause developmental damage in the fetus. Toluene has also been linked to immune system toxicity. It can be found in nail polish, nail treatments and hair color/bleaching products.

Propylene glycol. Propylene glycol is a small organic alcohol commonly used as a skin-conditioning agent. It’s classified as a skin irritant and penetrator. It has been associated with causing dermatitis as well as hives in humans — these sensitization effects can be manifested at propylene glycol concentrations as low as 2 percent. It can be found in moisturizers, sunscreen, makeup products, conditioners, shampoo and hair sprays.

Sunscreen chemicals. These chemicals function as a sunscreen agent to absorb ultraviolet light. These chemicals are endocrine disruptors and are believed to be easily absorbed into the body. They may also cause cellular damage and cancer in the body. Common names are benzophenone, PABA, avobenzone, homosalate and ethoxycinnmate. They can be found in sunscreen products.

It’s impossible to avoid every single synthetic chemical, but you can do your part in limiting the amount of toxins your body is exposed to.

Educate yourself and do your research before you buy. Think of something you absolutely love, and the time and energy you apply to it. Use the same, when it comes to your health. You have one life to live and one body. If you don’t take care of yourself, you may pay for it later in sickness.

Toulison Nutraceuticals Inc., was created to provide their clients with natural care products this is why we intentionally specify that our creams, lotions or body butters contain only natural ingredients and no chemicals preservatives at all.

Our company developed natural preservative formula to provide a decent life-shelf to our products, as well as exclude any probability of side effects due to high toxicity of traditionally used compounds. In our next blog, we will talk about natural substances that carry preservative properties and are not only harmless but also beneficial for skin.


The “terminology” used in the silver supplement market has truly become confusing, frustrating and many times downright misleading. Sadly, between well-meaning manufacturers who honestly don’t know the difference between the two main types of silver (or what they are actually producing) to those who knowingly mislead the consumer through deceptive claims and pseudo-science, it’s rare to find a general consumer that could actually know the difference between the two main types of silver solutions.

Colloidal Silver: Colloidal silver can be defined as a silver solution that is comprised of a majority of silver particles. Silver particles are pure pieces of silver metal that are neither ionic nor bound to any other constituents such as chloride, Cl or oxygen O (forming AgO/Ag2O or AgCl for example.) The word “colloidal” is the most misrepresented term for almost all silver solutions produced today. First of all, the general consumer only knows one word concerning silver solutions; that word is “colloidal.” It is safe to say that 9 out of 10 consumers have never even heard of the term “ionic”, which is what 90% of all silver solutions sold today actually are.

Ionic Silver: Ionic silver can be defined as a concentration of silver ions (Ag+) suspended in highly purified water where the majority of the solution is comprised of positively charged silver atoms. When a silver atom loses one or more of its negatively charged electrons, it is now termed as an ion of silver that carries a positive charge because the protons of its structure now outnumber the electrons. Realistically, 90% of all silver solutions marketed as colloidal are absolutely not colloidal by proper definition of the term and are in fact almost entirely ionic.

Ionic vs. Colloidal: Although most silver solutions sold today are actually ionic solutions (and misbranded as colloidal), this doesn’t mean that ionic silver is without merit or less effective than true colloidal silver. In fact, both forms are valuable based on the administration method chosen. Silver solutions can be administered in vivo (inside of the body) or in vitro (outside of the body) – topically. This is why there is value in knowing the difference between the two types and why having the ability to produce (both forms) of these two silver solutions is an invaluable luxury to the (educated) silver supplementing consumer.

Diverse applications of different types of silver solution:true colloidal silver solution that is comprised of nanoparticles of pure silver metal that are less than 40 nanometres in diameter will exhibit a yellow hue. If the concentration of a true colloidal silver solution moves into the 15 PPM range of concentration or greater, the color will fade into a deep amber and then brown depending on how far beyond 15 PPM of concentration the solution is. This yellow color occurs because silver nanoparticles that are in this size range absorb the blue/violet/indigo spectrum of white light and thus reflect all other colors (except for) the spectrum that has been absorbed. This phenomenon of particle physics is called “plasmon absorption resonance” and is not a theory but rather a very well- understood attribute due to the presence of silver nanoparticles in solution.

This is why true colloidal silver (meaning complete pieces of silver metal that are neither ionic nor bound to any other agents) is the species of choice (in vivo), as pure metal particles of silver do not form weaker chemical compounds of silver anywhere in the body( like silver chloride AgCl or silver oxide AgO/Ag2O, which ,by the way, is extremely unstable).

In summary, ionic silver solutions are best suited for low (or no) chloride environments, preferably topical use, while true colloidal solutions (particles of pure metal) are the species of choice for chloride-rich environments such as the stomach and blood and can be taken orally with keeping their high efficiency.

How Colloidal Silver Benefits Work 

According to a report written by Richard Davies and Samuel Etris of The Silver Institute in  1996, there are three primary ways how colloidal silver can serve as a natural healing solution:

  1. Catalytic Oxidation: Silver naturally holds onto oxygen molecules, which readily react with the sulfhydral (H) groups that surround bacteria and viruses. In turn, this helps block the life-preserving cellular process known as cellular respiration, which is defined as a set of metabolic reactions and processes that take place in the cells of organisms to convert biochemical energy from nutrients into adenosine triphosphate (ATP) and then release waste products.
  2. Reaction with Bacterial Cell Membranes: Silver ions can attach to bacteria cell membranes directly and produce the same respiration-blocking effect.
  3. Binding with DNA: Shown to literally enter bacteria DNA, up to 12% of silver has been detected in Pseudomonas aeruginosa. According to one source, while it remains unclear exactly how the silver binds to the DNA without destroying the hydrogen bonds holding the lattice together, it, nevertheless, prevents the DNA from unwinding, an essential step for cellular replication to occur.

These processes define the following preservative properties of colloidal water.

Antibacterial

Colloidal silver, unlike its modern prescription antibiotic counterpart, simply doesn’t create resistance or immunity in the organisms that are killed by it.

Anti-viral

Colloidal silver suffocates the virus and can even reduce the activity of the HIV virus in AIDS patients. There are also numerous anecdotal accounts of colloidal silver’s efficacy against the hepatitis C virus.

Anti-inflammatory

Colloidal silver is also a fantastic anti-inflammatory remedy. Case in point: researchers at the National Institutes of Health (NIH) studied the effects of inflammation after being treated by colloidal silver; they found that the inflamed skin of pigs treated with silver experienced near-normal skin after 72 hours, while other treatment groups not treated with silver remained inflamed.

Research is beginning to reflect what many people have already known for years — that colloidal silver can reduce swelling, speed healing, and boosts cell recovery!

Anti-cancer

In 2010, the group of scientists published a paper in Journal of Experimental & Clinical Cancer Research where anti-cancer properties of colloidal silver water were shown. The scientific study was performed on the MCF-7 human breast cancer cell line with the results showing a dose dependent cytotoxic effect through induction of apoptosis and cell death.

In July of 2017, our company, Toulison Nutraceuticals Inc., obtained same results in experiments with the human breast cancer cell line, using the colloidal silver water manufactured by the company. There are data below on dose dependent (exponential) cytotoxic effect of colloidal silver water in wound scratch cell migration assay tested in human breast cancer cells.

Next, we will present regular water and colloidal silver water.

Below, we project a red laser light thru regular water. This illustrates that there are no particles suspended in the water. In other words, the light does not bounce off an anything.

Next, we project the same red laser light thru colloidal silver water. Here we see the red light beam reflect off of the silver particles suspended within the processed water. Note: Colloidal means particles suspended within a solution.

Lastly, Dr. Anna Toulina discusses the value of colloidal silver water.